I don't see why you'd need to readjust it. If the safety engages properly as is, and you will still be using the race hammer it should be fine. The adjustment is just for safety engagement, nothing more.
Yup. It doesn't adjust the engagement of the sear/hammer.
It adjusts to keep the sear from moving when the trigger bar makes contact with it. Or rather, adjusts so that the safety, when in the SAFE position, keeps the sear from moving. When you "adjust" the screw that's what you're doing. You turn the screw "down" till the cam on the left side safety shaft makes contact with the tip/bottom of the screw.
I can tell you, the adjustable sear beats the heck out of doing it the old fashioned way (stoning metal off the cam lobe to properly mesh with the arm on the sear (BTDT).
Check it to be sure though. The race hammer will have a much shallower notch than most of the factory hammers so the sear won't have to move as much to release it. As long as the distance from the hammer pin to the bottom of that notch is similar to the factory hammer you may find no adjustment is necessary.
This stuff is fun, working on your pistol and learning stuff, I mean.