I finally got a chance to take apart a decocker version. Yes, the hole is in the exact same spot as the safety's is. The ONLY thing that looks like would need to be done, is to machine out the section of the frame where the small saftey keeper is (best term I could come up with). Bascially the small spring and piece that keeps the safety either on or off. That cut was not made in the frame.
BTW, where do people get the idea that a SA gun is more accurate than a DA/SA gun? There is NOTHING different about the guns accuracy, only the trigger pull the SHOOTER feels. That is a training issue, not a gun issue. And, the SA pull that developed after about 4000 rounds through my CZ is good enough for ANY defensive shooting situation. It may not be a bullseye type trigger, but it is more than useable for combat.