CZ85 is full ambi, both safety and slide release. CZ85's come in 2 flavors. CZ85B is an ambi CZ75B and has a firing pin block. A CZ85 Combat has a better, out of the box, trigger and no firing pin block. Both can be used for almost anything you might want a pistol for. For me, they are bigger/heavier than I'd want to carry. I own a tricked out CZ85B. I'm not left handed. At the time, it was the only full sized CZ I could find. I used it for USPSA competition for a little over a year.
The SP-01 has a full length dust cover and a rail, for a light, and has ambi safety but not slide release. Both of these guns are all steel construction. They come as either the standard, with a firing pin block, or the Shadow, without. These are heavier than the CZ85. To me this is a service weapon, night stand gun or recreational gun. I have a Shadow for USPSA.
Some of the compact models also have ambi safeties or decockers. Read closely at cz-usa web site for descriptions. Some compacts have steel frames and some have aluminum. I've never handled any of these.
CZ also makes some polymer frame pistols, the P-07 and the P-09. These can be easily switched from ambi decocker to ambi safety. Slide stop is left side only. P-07 is a compact gun. P-09 is a full size service weapon. Both have rails. A P-07 is on my list of likely future purchases.
