I agree that the US is the only big market for .45s, but it's also the LARGEST market for handguns, period.
I suspect that the good ol' 1911 -- the only true All American semi-auto handgun -- has caused too many folks to think that 8-rounds are totally sufficient for most .45 "events," and it might be.
For home- or self-defense you seldom hear (nor can you find evidence on line) of a shooting that takes more than 3-4 rounds fired by the good guy. If you did, you'd probably see more folks carrying backup magazines. The Ellifritz study, which is quite large, shows that most civilian shootings are seldom more than 2-4 shots fired.
But that's true of 9mms and .40s involved in shootings too, but those guns are far more popular in the gun games where lots of rounds are important. I think the gun games drive a lot of the features we see on newer handguns. Even if you don't need 17 rounds, extended mag releases, or clean triggers with short resets, those things are seldom a hindrance.
I think marketers selling guns use the same psychology and techniques we see used when selling cars -- it's often more about IMAGE than true function or performance.