Isn't this type of problem fun? I had a S&W model 10 that was unopenable and had a full load of old bullets. I ended up soaking the gun in light machine oil for about 3 months to deactivate the powder, then malleting the cylinder open. I also had to do the following with a 45, though I new the round was a dud, as I seated a bullet in a spent case. In your case, I would first ask a good gunsmith what to do, and if they can fix it. If you or they don't want to do that, I would take the slide section off and soak the whole thing like I did. Then when you think the possible live round is dead due too the oil, try to remove the round. I would remove the fireing pin first. Then if you can get the barrel out, that might do it. If the barrel dosn't come out, re-assemble the gun minus the grips, clamp it into a padded vise(Use soft wood, leather, or heavy cloth to padd the vise). After that, drill a whole a little bigger than the barrel in a board, and use a mallet to hit the board, with the board lined up whole to barrel. Be careful, and go slow. you should be able to tap the slide back. Same idea differnt way is to use a hardwood dowel down the barrel, and try to tap the round out directly. I would be very careful, and wear eye and ear protection, and don't place yourself or anything valuable (like family) in line with the barrel. If you can do this a a range, do so. A warning! I am NOT a gun smith! And even though I have used all these methods, USE THESE METHODS AT YOUR OWN RISK, AND ONLY AFTER CHECKING WITH A GUN SMITH FOR OTHER OPTIONS/OPINIONS!!!