I have relatively small hands myself, and yes the grip frame of the 97B (in my case) is a large one. It's a superb weapon in every regard, but I had to make certain adaptations to it. For one, I can't maintain a proper firing grip and operate the manual safety with one hand, nor can I use the double-action trigger very easily with one hand. I did learn how to quickly operate the safety and go back to the firing grip one-handed, and for any situation that would require a quick double action shot I could manage it, but for the most part I have reconciled myself to operating the pistol with two hands. In that manner, the heft, balance and accuracy of the gun made me fall in love with it. I've read accounts of them being sensitive to HP ammunition, but I wouldn't know because I use nothing but RN hardball in it (and don't feel in any way handicapped). It has been perfectly reliable. I guess the salient points to you would be that it's a great gun, that carries ten + 1 rounds of a great cartridge. As I share your fondness for the 75, I will also tell you that nothing will compare with the ergonomics (save the P-01) of that wonderful piece. Good luck.