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I tried it in .45 and did not care for it. It took over 6 grns to get me Power factor of 167 which is too close for comfort and the recoil felt extreme.This was with Bayou 200gr SWC bullets at 1.265.I liked it pretty well in 9mm.Your results might be different.Good Luck!
Just curious as Hodgdon starts out at 6.5 for 1.225 COL.