I have used the Warne Maxima medium QD on my 527 Carbine with a Leupold VX-I 2-7x33 scope to good affect. The bolt handle is the new, low profile, style and I have about 0.1" clearance between the handle and the eyepiece. However, the Nikon you mention has an eyepiece diameter of 1.73" where my Leupold is 1.56". A quick calculation shows you would end up with .015" of clearance, which seems pretty snug.
Edit to change estimate of clearance for the Nikon scope.