It really depends. There are times when I wonder why I own anything other than a P07 since those feel so good. Then I?ll spend some time with a P10C and before long, it will be the 75B Compact, P01 and 99021 that each seems like the best blend of everything. They all are really good and all are duty grade weapons that will last a lifetime.
For carry, I like a pistol with a decocker but either safety or striker fired are good too. Other than that, they are all solid choices. If I could only have one gun, it would probably be a P01 with the 16 round mags and SP01 base plates. Wait, make that the 75B Compact.