I am a lefty and my sole reason for owning them is due to the ambi safety, as it’s one of the few ways to get the classic CZ 75 design (standard service gun with no rails, etc) with ambi controls.. I could care less about the ambi slide stop. The Ambi slide stop only serves to add an extra part, and is not a great design either IMO.
The 85 and 85 Combat are great guns, and a good way to get ambi controls on the classic CZ 75, but in this day and age the newer models mostly sport ambi controls (Shadows, SP01, stainless, etc) as it is. The only safety guns I can think of that still have single sided safeties are the regular 75B full size and Compact.
I am saddened by the loss of the 85 Combat though, for the longest time it was a great starting point for building your own Shadow-like gun due to the lack of FPB.