If you've really got to have different sights, have a gunsmith mill a dovetail in the front of the slide, and select an appropriate after market sight and install it. Changing out the rear sight at the same time might not be a bad idea.
It won't cost THAT much for that little bit of work. And it shouldn't be necessary to refinish the slide for that little bit of work. (The gunsmith or you can simply use "cold blue" on the cut area. Touch it up from time to time, if necessary.)
I've had this done a couple of times on guns that had "integral" front sights: a Beretta 96 and a S&W 669. The hard part, which the gunsmith should be able to handle, is selecting a front sight of the proper heighth.
I don't think it would be a good idea to try to drill and insert tritium inserts. That's a very specialized application. If you've got the equipment and knowhow to drill that precisely, you can install proper sights. Finding the inserts may be a problem, too.
(One of the difficulties experienced with some night sights is that the tritium inserts tend to work loose after being exposed to solvents, etc. A home-job, not using the right glues, etc., is likely to lead to insert flying out while firing, etc.)