I recently bought a new P-01 Omega and it has not had any issues in over 200 rounds of Re-manufactured 147gr, 124gr and 115gr. Defender ammo, as well as some 115 gr Blazer.
FYI: My last CZ 75B Omega had some issues with failure to fire, where the there were no visible marks on the ammo primer and CZ "lengthend the throat". Whatever that is, it worked.